Whatever the problem is, the fact remains that maya 8.0 is just not the best to work with. I have had 4-8 crashes a day, one of which cost me 3 hours of modelling work, just cause "bevel poly" couldn't handle it. In Maya 7.0 it would have just given me a warning.
Maya 8.0 is really unstable. Use 7.0 or 8.5 if you have the option.
Have you experienced frequent crashes in maya 8.0 or is it just me?
I have also had some " UI goes crazy " situations with 8.0.
I use 8.5 for months now and it has crashed only 4-5 times overall.
Anyway, since you dont use hotkeys, you wouldn't care much if everything whas reset?
gentlesea is right, that mostly solves all the ui related problems. what happens is that maya will recreate a default UI and presets folder if it doesnt find it in "My Documents". Careful not to delete your scenes though... there in that folder too if u used the default project.