I'm assuming you are building half of a missile and want to combine it and mirror it...
If that's the case, combine your duplicated geometry, make sure it's verticies are merged, then duplicate special the missle to the otherside. If you combine that new geometry (the mirrored missle) to the original, select it at vert level and then make sure your manipulator is set to mirror mode. You will then be able to move both sides of the missile at once.
If you want to post an image of what you're working on, I'll be more than happy to help you a bit more.